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The 28-year-old is rated as one of the best defenders in Europe and has a long list of clubs interested in his services.
It was believed he would cost an extraordinary amount of money but the coronavirus pandemic will likely have a huge impact on the summer transfer window.
Among the sides linked with Koulibaly are Manchester United and Manchester City as well as current Premier League leaders Liverpool.
Despite this, De Laurentiis addressed a transfer for the Senegalese international in trademark fashion.
"If City or United or PSG with €100 million (£90 million) showed up, I would think about it [selling Koulibaly] and it is probable that they [the player] would leave, always if their will was to leave," the 71-year-old told Corriere dello Sport.
"I don't even consider an offer of €60 million (£55 million). I am solid, if I wanted to win the Scudetto at any cost today I would find myself with three, four hundred million debts.
"I look around and see companies at €500, €600 million, less a billion. I don't owe anyone a s**t."
Napoli sporting director Cristiano Giuntoli also recently stated: "Kalidou is a great player, who still has a long contract with us.
"If we were to sell, the club could ask for a large sum. A player like this cannot change his value even in a crisis, so we are not moving our valuation."
One man who is likely to remain with the Naples side this summer is Dries Mertens.
The Belgian forward was targeted by Chelsea in the January transfer window and he has been offered a new deal by the Serie A side.
He became the club's all-time top goalscorer on Saturday, with his strike against Inter Milan in the Coppa Italia taking him ahead of Marek Hamsik in the standings.
De Laurentiis sung the 33-year-old's praises and called him a 'badass'.
"He is a street urchin. We met for breakfast six months ago, it was a revelation, I discovered a special man, intelligent, mentally sharp, a badass.
"Renewing the contract for a 33-year-old footballer is not part of our habits, but with Mertens it was simple, natural. I will say more when he has stopped playing, I would like to find him a role to continue the collaboration."
Featured Image Credit: PA Images
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