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The Red Devils travelled to the Emirates on Saturday as they aim to bounce back from their shock Premier League defeat to Sheffield United earlier this week.
But McTominay looked uncomfortable early in the first half and was struggling as he clutched his stomach.
United boss Ole Gunnar Solskjaer decided to withdraw the 24-year-old Scottish midfielder before half-time by bringing on Anthony Martial in his place.
However, that hasn't stopped some fans from speculating that McTominay was in desperate need to visit little boys' room ahead of half-time.
"McTominay looks like he's facked [sic]," one fan posted.
While another Twitter user wrote: "Take McTominay off, looks like he's carrying a knock."
A third tweeted: "McTominay is clearly injured so we going to just keep him on?"
And a fourth added: "McTominay clearly struggling and has been for some time now. Get him off the pitch ffs. Don't wait until half time Ole."
Full-time result: Arsenal and Manchester United shared the points as the Premier League match ended 0-0 at the Emirates.
United remain second in the Premier League, while Arsenal are eighth in the league table and are six points off from the top four.
Featured Image Credit: Sky Sports
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