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Ronaldo, 37, is seeking to leave United this summer in order to play Champions League football this season.
A number of clubs, including Chelsea, Atletico Madrid and Bayern Munich, were linked with the Portuguese star earlier this summer but have since cooled their interest in the five-time Ballon d'Or winner.
With his options looking short, fans have speculated whether Ronaldo could return to his former club Real Madrid.
Ronaldo is the top scorer in Madrid's illustrious history, having bagged an incredible 450 goals in 438 games for the Spanish champions during a hugely successful nine-year spell at the Bernabeu.
But current club president Perez, who signed Ronaldo in a £80m deal from United back in 2009, has all-but ruled out a move for the Portugal international.
When asked by fans if he plans to make a bid for the striker, who still has one year left on his current deal at Old Trafford, Perez replied: "Sign Cristiano? Again? He's 38 years old", getting the age of the striker wrong.
Ronaldo missed the majority of United's pre-season preparations after handing in a transfer request last month and was only deemed fit enough to start from the bench in the club's opening game of the season against Brighton on Sunday.
Red Devils manager Erik ten Hag introduced Ronaldo in the second half but the forward was unable to find the net, as United suffered a disappointing 2-1 defeat at Old Trafford.
After the match, Ten Hag admitted he was wrong to bench Ronaldo, starting Christian Eriksen in an unfamiliar 'false nine' role instead.
"It is clear to see [that in] the second half we were better in midfield with Eriksen down and Ronaldo up," Ten Hag said.
"We created and Rashford had two good chances, it is a shame we did not score."
Meanwhile, a new report claims that Ronaldo's teammates are becoming increasingly annoyed by the player and his desire to leave.
According to The Sun, some of his "fed up" colleagues would prefer it if he left the club rather than the current situation.
The report claims there is a growing anger amongst the squad members at Ronaldo's attitude around the club.
A source said: "It is really starting to annoy a lot of players now.
"He does have his allies in the camp but a lot are fed up with how he is going about things."