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Spain are the red hot favourites to qualify top of Group E, but their Scandinavian opponents will be keen to capitalise on their pre-tournament issues.
Enrique has also had to deal with multiple positive coronavirus tests within the camp, with captain Sergio Busquets among those affected.
Spain have since called up 17 players to train in a 'parallel bubble' - but Sweden have had issues, too, as both Dejan Kulusevski and Mattias Svanburg tested positive for coronavirus themselves.
:rotating_light:¡¡HOY DEBUTAMOS!! :rotating_light:
:soccer: España - Suecia
:trophy: Fase de Grupos de la #EURO2020
:clock9: 21:00 (hora peninsular española)
✍️ https://t.co/cr059FxzN9#SomosEspaña pic.twitter.com/5pkuEgdY0M
- Selección Española de Fútbol (@SeFutbol) June 14, 2021
La Roja have won this competition on three previous occasions - level with Germany - and will now be looking to move out alone in terms of trophies, having triumphed in 1964, 2008 and 2012.
Can they do it again? Well, they're certainly not to be underestimated, that's for sure.
With this summer's tournament now in full swing, our tipster Robert Mann takes a look at some of the best bets from Spain vs Sweden to get your teeth stuck into.
Spain are 1/3 to win, with Sweden priced at 8/1 to come away with the victory. A draw is priced at 4/1.
Prediction: 3-0 (15/2)
Half-Time/Full-Time Spain/Spain (1/1)
The nation still boasts, however, a hugely talented midfield, but they are more of an up-tempo side than squads of the past.
Despite a completely new look, La Roja will still be one of the main threats during this year's contest and we reckon they could make a statement against Sweden this evening.
On that basis, we think that Spain to lead at half-time and claim the three points by the final whistle sounds like a solid bet.
First goalscorer: Ferran Torres (4/1)
Highly regarded by manager Luis Enrique, the 21-year-old scored a hat-trick in the 6-0 thrashing of Germany earlier in the year.
The starlet is one to watch during this summer's showpiece and could very well force his way into Guardiola's plans for next year's Premier League season.
Request A Bet: Morata 2+ shots on target & Torres 1+ shots on target (2/1)
Spain's main concern may be lacking elite quality in front of goal, but Alvaro Morato certainly knows how to find the back of the net.
The Juventus forward brings plenty to the side and, if he is given the service that he so dearly craves, then we reckon he can bang in the goals this summer.
Ferran Torres should be lively on the wing for Spain, too, with the pair more than likely to be a nightmare for the Sweden defence this evening.
Odds are correct at the time of publication and are, as always, subject to change.
Please gamble responsibly. For more information visit: https://www.begambleaware.org.
The 2008 and 2012 European champions are without captain Sergio Busquets after he tested positive for coronavirus.
:stuck_out_tongue_winking_eye: ¡¡APRÉNDETELAS Y CANTA LOS GOLES CON NOSOTROS!!
:raised_hands: Estas son las celebraciones que esperamos compartir MUCHAS VECES durante esta #EURO2020.
Seguro que este vídeo os hará tanta ilusión como a los jugadores grabarlo para vosotros.
:muscle: ¡¡VAMOS, #ESP!!#SomosEspaña pic.twitter.com/osexIu4tKY
- Selección Española de Fútbol (@SeFutbol) June 13, 2021
Sweden will be without Dejan Kulusevski and Mattias Svanberg, who have also both tested positive for coronavirus.
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