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Mayweather claimed he was the greatest boxer in history, better than the likes of Ali and Tyson who hit back in brutal fashion.
"He's very delusional," 'Iron Mike' explained. "Listen, if he was anywhere near that realm of great as Muhammad Ali, he'd be able to take his kids to school by himself.
"OK, he can't take his kids to school by himself, and he's talking about he's great?
"Greatness is not guarding yourself from the people. It's being accepted by the people.
"He can't take his kids alone to school by himself. He's a little scared man. He's a very small, scared man."
Tyson has previously had some beef with Mayweather and when he was asked about a potential street fight with him in his prime, he told GQ: "[I would] kick Floyd's a**e... there wouldn't even be no match."
The former undisputed heavyweight champion put his rivalry to one side with Mayweather when he suggested that he'd lose in a boxing fight if he were the same size as him.
He revealed: "[If] I was his size in the ring, he would outpoint me."
It's clear to see Tyson's respect for the late Ali, and he once broke down mid-interview when discussing his life and career.
He appeared on Michael Rapaport's podcast in March 2019 and candidly discussed 'The Greatest'.
"I always like to think I'm a bad motherf**ker. A vicious motherf**ker," he begun.
"I don't give a f**k, but that's the part where Ali overshines me, because I can't understand a man that's willing to die for this. I talked the sh*t, but he's the real deal."
The 55-year-old then dubs Ali 'a giant' as he fights back tears.
"Ali is a giant. There's no way other fighters can match him. He'd die for this sh*t. I'm not going to die for this. That's real talk. Ali is a savage, he's an animal. He's a different breed of person. He's not like us."
What do you think of Floyd Mayweather's claims? Who is the greatest of all time?
Let us know in the comments.
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