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Rafael Benitez's side have showed early promising signs during his short tenure and have won two of their opening three matches and remain unbeaten.
The Clarets will want to get points on the board early and avoid the potential of getting dragged into a relegation scrap, however, Everton harbour their own aspirations of challenging for a European place.
Ahead of the game, our tipster Robert Mann takes a look at some of the best bets from Everton vs Burnley to get your teeth stuck into.
Everton are 4/6 to win, with Burnley priced at 9/2 to come away with the victory. A draw is priced at 13/5.
Prediction: 2-1 (7/1)
First Goalscorer: Demarai Gray (6/1)
Having scored in just two of his previous 32 appearances, Demarai Gray has founded the back of the net twice in his three appearances for Everton.
His creativity and flair could offer one or two issues for Sean Dyche's Burnley and we're backing the 25-year-old to draw first blood tonight.
To Score 2+ Goals: Everton (10/11)
Everton have scored at least twice in each league match so far this campaign and there are signs that Benitez is instilling the consistency that the Merseyside outfit need.
Headed Shot On Target: Dominic Calvert-Lewin (5/6)
Calvert-Lewin has been in excellent form for Everton over the past year and has proven himself to be almost unstoppable in the air.
He scored a header against Southampton on the opening day of the season and there’s no reason why he can’t repeat that feat again tonight.
Odds are correct at the time of publication and are, as always, subject to change.
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Calvert-Lewin was forced to withdraw from the England squad over the international break due to a quadricep problem, but Benitez has revealed that the striker could feature here.
Should Dwight McNeil feature, he will become the youngest player to play 100 Premier League games for Burnley at just 21 years and 295 days of age.
Elsewhere, new signing Maxwel Cornet may have to wait a little longer for his debut due to a dead leg, while Connor Roberts, Dale Stephens and Kevin Long should start.
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