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The two teams finished ninth and 11th in the league last year, with the Seagulls enjoying a strong start and finish to the season - whilst the Magpies collected the sixth most points in the league after the appointment of Howe, who replaced Steve Bruce at the helm.
Both sides also enjoyed fantastic starts to their 2022/23 campaign. Newcastle enjoyed a comfortable 2-0 win over newly promoted Nottingham Forest, with Fabian Schar scoring a stunner from long-range before Callum Wilson netted his opening goal of the campaign.
Brighton travelled to Old Trafford in Erik ten Hag’s first fixture in charge and spoiled the party, defeating Manchester United 2-1. Pascal Gross scored twice as the Seagulls upset the odds against the 20-time league winners.
Here’s everything you need to know about Brighton and Hove Albion vs Newcastle United.
The game won't be shown live on television. but you can watch studio updates of the match on BT Sport and BBC Final Score and stream the match via Peacock Premium if watching in the USA.
Fans can also see the highlights on BBC Match of the Day.
The match will kick off at 3 pm BST at the Amex Stadium, Brighton.
The Seagulls will be without Jakub Moder, who will be out for a long time with a ‘complex and severe’ anterior cruciate ligament injury - yet didn’t seem to miss him or the departed duo Yves Bissouma and Marc Cucurella in their win over United.
Apart from him, it is a clean bill of health for Potter’s men.
Jonjo Shelvey will be sidelined for a long period of time after undergoing hamstring surgery at the beginning of this month. Javi Manquillo, Jamal Lewis, Federico Fernandez, Emil Krafth and Jamaal Lascelles are all in a battle to be fit for the fixture.