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McGregor, 32, stopped Poirier in stunning fashion in their first fight at UFC 178 in Las Vegas in 2014.
Fast-forward to January 2021 and Poirier bounced back to seal a sensational second-round TKO win over McGregor at UFC 257 in Abu Dhabi.
McGregor and Poirier will now complete their trilogy of fights when they return to the octagon at UFC 264 on 10th July in Las Vegas.
Back-to-back defeats for McGregor could leave his future in MMA uncertain and potentially spell the end of his career in the sport.
That is according to Fury, who claimed this could be the future UFC Hall of Famer's "final roll of the dice."
Speaking to UFC legend Michael Bisping on BT Sport, the WBC champ said: "It's Conor McGregor's final roll of the dice.
"If he loses this one, it's curtains, isn't it? I think he wins this one and I think he wins it in style, to be fair."
Fury, 32, is set to make the first defence of his WBC title against fierce rival Deontay Wilder on 24th July in Las Vegas.
McGregor has been training hard for the third Poirier fight as he has teased MMA fans with his preparation for the UFC 264 showdown on social media.
However, the Irishman previously admitted he lost concentration in the build-up to a fight, specifically when he was drinking ahead of the Khabib Nurmagomedov clash at UFC 229.
Fury has been vocal about his battle with alcoholism, drugs and mental health issues during his hiatus from boxing.
The Gypsy King said that he has heard McGregor "lives like a rock star when he's like a week away from his fight," but he insisted that the Notorious should not live that lifestyle when he is in training camp.
Fury explained: "With Conor, you never know what he's been doing. You never know what he's been up to in training camps and all that.
"From what I hear, he lives like a rock star when he's like a week away from his fight, so you can't do that. When I'm in a training camp, I'm 100 per cent dedicated to the fight.
"I don't do anything, I go to bed early, wake up early, don't drink anything but water, I'm 100 per cent dedicated to the job in hand.
"If I'm going out getting smashed in the nights before a fight, then I'm asking to lose."
Featured Image Credit: BT Sport/Dustin Poirier & Conor McGregor's Instagram
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