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Both sides started off the new season poorly last weekend, with Forest losing 2-0 at Newcastle and the Hammers being defeated by Man City by the same scoreline.
West Ham go into this game favourites, and according to the BBC, Forest have won only two of their past 21 league fixtures against the East London club.
Here's everything you need to know about the game.
Yes, Forest vs the Hammers will be shown live on Sky Sports Main Event and Sky Sports Premier League.
Fans can stream the action on the Sky Go App, but you must have a subscription for Sky Sports.
Steve Cooper's side will be without defender Scott McKenna, Ryan Yates and Steve Cook for the game.
Star forward Michail Antonio is back after the small injury he suffered against Man City last weekend.
However, Goalkeeper Lukasz Fabianski who came off in that match may not feature.
Hammers boss David Moyes announced this week that new signings Maxwel Cornet and Gianluca Scamacca are ready to start.