Southampton midfielder Alex Jankewitz was sent off just 79 seconds into his first ever start for the club, after his challenge on Manchester United's Scott McTominay.
Ralph Hasenhuttl's side have been hit with a bit of an injury crisis recently, leading the Saints boss to struggle with team selection for their trip to Old Trafford.
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The south coast side had two goalkeepers on the benchm to really punctuate their issues, and 19-year-old Jankewitz was making his first start.
The Swiss midfielder only made his Premier League debut as a substitute on January 30th against Aston Villa, playing the final minute of normal time and injury time.
When he started on Tuesday he probably expected he'd get more game time but it turned out not to be the case, with his horror challenge on McTominay, which left the Scotsman with a mark high on high thigh.
United, who rested Paul Pogba on the day he was named the club's Player of the Month for January, were in need of a victory after a tough week.
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Ole Gunnar Solskjaer's team lost to Sheffield United last week and drew 0-0 with Arsenal at the weekend but it didn't take them long to benefit from Southampton's early red card.
Luke Shaw's deep cross found Aaron Wan-Bissaka at the far post, with the right back stabbing home from close to the goal after just 18 minutes.
Jankewitz could at least take some heart from the fact even more experienced players manage to get themselves sent off doing silly things, with Bernd Leno being sent off for Arsenal earlier in the night.
Featured Image Credit: BT SportTopics:ย Football News, Manchester United, Southampton, Premier League