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All three of England's games will be held at Wembley, as will the semi-finals and final of the tournament.
So, when will Southgate be giving players the green or red light?
Gareth Southgate will announce his Euro 2020 squad at 1pm on Tuesday, 25 May before holding a press conference from St George's Park to explain his selections.
All 24 nations competing at the finals must submit their squads by 1 June, ten days before the start of the tournament.
UEFA recently expanded the number of players in each squad from 23 to 26, in order to cover the risk of players being ruled out through positive COVID-19 tests or quarantine regulations during the tournament.
It is unclear whether Southgate will name a full 26-man squad or merely select three additional players to be on standby.
The England manager was sceptical about the prospect of expanded squads when asked during the March international break.
Every squad must include three goalkeepers.
If a player is ruled out of the tournament through injury before their teams' first match of the tournament, they can be replaced.
Goalkeepers ruled out through injury are able to be replaced at any time.
Players who are replaced cannot be readmitted to the squad later in the tournament.
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