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The result means the north London club have won just two of their last seven games in all competitions.
Currently sitting in ninth in the table, a win would move them level with Everton and just six points off fourth place.
The Toffees are also going through their own rough patch of form and are winless in their last six games in all competitions, including a draw in each of their last three games.
The Merseyside club currently sits eighth in the table, but a win would put them just three points off the top four, with a game in hand over the teams around them.
The match will be shown live on Sky Sports Main Event and Premier League, with coverage starting from 7pm (BST) before the match kicks off at 8pm.
Subscribers can stream the match via the Sky Go app, however, if you're not a Sky customer you can grab a NOW TV Day Pass here to watch without a subscription.
Both sides have quality among their ranks, but their current form wouldn't necessarily suggest that.
Arteta will be keen to get his side firing ahead of their Europa League semi-final clash next week, while Everton still have a very real chance of making the top four if they can get back on the winning trail.
Ultimately, with neither side at their best, and with their best attackers being unavailable or not fully fit, it likely means the game will lack goals too.
Arsenal are 21/20 to win in midweek, with Everton priced at 13/5 to come away with the victory. A draw is priced at 12/5.
Odds are correct at the time of publication and are subject to change.
The Gunners are set to be without both of their first choice strikers following their draw with Fulham.
Pierre-Emerick Aubameyang is still recovering after contracting malaria on international duty for Gabon, while Alexandre Lacazette hobbled off in the second half with a hamstring injury at the weekend.
With the two star forwards missing, Eddie Nketiah should get the nod from Arteta after scoring on Sunday.
The England international has missed the last two games with injury and while Everton expect him to be available against Arsenal, it's unlikely that he'll start.
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