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And ahead of the official August 14 launch on PlayStation and Xbox One, it's now been have confirmed that the pair of British world heavyweight champions have virtually crossed over into the UFC in the new video game.
It means that fight fans can pit WBA (Super), IBF, WBO, and IBO champion Joshua against UFC's heavy-hitting Francis Ngannou inside the Octagon, or even see how WBC world champion Fury would fare in MMA having dabbled in some training with UFC middleweight Darren Till.
Joshua and Fury, who have agreed terms for a two-fight deal inside the squared circle in the future, can be accessed through pre-ordering the game.
"Fighting is what I have dedicated myself to. No matter the stage or opponent, I'll always back myself," Joshua said, reflecting on his appearance in the game.
"My character in UFC 4 will be no different. I'm looking forward to picking up the controller and dominating UFC 4."
"I have a lot of respect for the UFC fighters but I'm the greatest fighter in the world," Fury added.
"It's going to be exciting to watch players use my boxing skills to outshine the most talented MMA fighters
in UFC 4."
Reflecting on how the addition of the two boxing superstars in the game came about, UFC 4 Creative Director Brian Hayes told SPORTbible: "It's fun to have characters in the game from a fantasy standpoint.
"To be able to casually and virtually explore what it would be like to take someone like Anthony Joshua or Tyson Fury into the Octagon and have a go, it's just good video game fun.
"When fighters like that are willing to work with us and interested in being in the product, we're stoked about it. We know that fighters like Bruce Lee and Mike Tyson have been really popular in the game so just thought about who are two big personalities in the boxing world that we could bring into the experience this year.
"They are the two names that come to the top of the list because heavyweight boxing is really seeing a resurgence. We settled on Joshua and Fury because they are massive superstars.
"For people that want another Fight Night game I'm not sure this completely bridges the gap but it does dip a toe in the water so to speak.
"With the options that we have in game, being able to play 'Stand and Bang' mode or Knockout mode it's strikes only. Then we have the ability with 'Blitz Battles' where we have a setting where it's potentially boxing only for a day and you take Tyson Fury and go in and piece people up.
"It's nice to have and it's way better than nothing, that's for sure."
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