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As all as being 50-0, Mayweather has also beaten a total of 23 world champions in his glittering career inside the squared circle.
One of those was of course Pacquiao, who Mayweather toppled in the 'Fight of the Century' with a unanimous points victory in 2015.
But 'Pac-man' is closing in on Mayweather's record, with his win over Keith Thurman his 22nd victory over a world champion holder back in July last year.
And with his inactivity, coupled with Pacquiao continuing to fight, Mayweather says he expects that particular record to be ousted in the near future.
"See they say, 'the great must fight the greats.' Well, just look in the history books. You'll see nobody beat more world champs than Floyd Mayweather," 'Money' told fighthype.com, via World Boxing News.
"Even with that being said, Pacquiao eventually probably would (beat that record). But guess what, Pacquiao was a professional before me.
"With everything he has accomplished. Hopefully, he's made some smart investments."
Mayweather went on a incredible, unprecedented run where he knocked off 16 world champions consecutively, including Pacquiao, Ricky Hatton, Saul 'Canelo' Alvarez and Oscar de La Hoya.
Earlier this month, a graphic of those greats that Mayweather beat begun doing the rounds and he elected to post it along with a message.
But instead of bragging about his achievements as he normally does, Mayweather ws humble and gave props to those he shared the ring with.
"I respect and take my hat off to every last one of these champions," Mayweather wrote.
Some of the very best fighters of the generation have failed to lay a glove on the 50-0 fighter with Mayweather's defensive skills and movement just unparalleled.
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