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And Ronaldo continued to inch closer to Ali Daei's all-time international goalscoring record as he buried a sensational second goal from outside of the box.
Pele, who won three World Cups and scored 77 goals for Brazil, congratulated the Portuguese forward as he continues to "reach new heights in your journey."
The 79-year-old football icon tweeted: "I thought we were going to celebrate 100 goals today.
"But it was actually 101! Congratulations @Cristiano, as you reach new heights in your journey."
Former Barcelona and Leicester City star Gary Lineker also hailed the "extraordinary" Ronaldo for reaching a "truly staggering achievement."
The 59-year-old Match of the Day presenter posted on Twitter: "Congratulations to @Cristiano on scoring 100 goals for Portugal.
"A truly staggering achievement by an extraordinary footballer. Well played."
Ronaldo, who won the Nations League with Portugal last summer, is now eight goals behind former Iran captain Daei.
Manchester United also took to Twitter to pay tribute to Ronaldo, who enjoyed glittering success at Old Trafford during his six years in the Premier League.
"Congratulations to @Cristiano on a century of international goals for @SelecaoPortugal," the Red Devils tweeted.
Featured Image Credit: PA
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