100 Men vs 'World’s Fastest Woman' Challenge for $100,000 Is Wild

Two-time Olympic medalist Melissa Jefferson-Wooden came up against 100 men in a $100,000 race on MrBeast's YouTube channel – and it made for a fascinating contest.

Jefferson-Wooden achieved a historic "triple crown" at the World Athletics Championships in Tokyo last month, winning gold in the 100m, 200m, and 4x100m relay.

Here, she delivered one of the most impressive 100m performances in recent memory, taking home gold after crossing the line in 10.61sec – a time that made her the fourth fastest woman in history.

The 24-year-old also completed the sprint double with a 200m win in 21.68 seconds before securing her third gold medal as part of the United States 4x100m team.

Two weeks on from her success at the National Stadium in Tokyo and Jefferson-Wooden was chosen to take part in MrBeast's latest YouTube video, which has picked up 35 million views in just 21 hours.

MrBeast, real name Jimmy Donaldson, brought together some of the world's best athletes for the video, including the world's strongest man, as they competed against groups of ordinary people.

Jefferson-Wooden was the first person to take part in a contest against 100 men to see who would win in a race. Asked if she was confident beforehand, she simply replied: "Yes".

Donaldson then announced that a cash prize of $100,000 was on the line if somebody could beat the five-time world champion.

As expected, Jefferson-Wooden would proceed to win the race, although several competitors were incredibly close behind, including number 35, who almost scooped the six-figure prize money.

"Number 35, you were actually not too far behind," Donaldson said, before asking if he did track and field. "No," he replied, before the YouTuber suggested he should probably try it out.

Mr. Beast made 100 random men RACE the world’s FASTEST Woman, Melissa Jefferson-Wooden for $100K, and it was CLOSE 😮🏃‍♀️👀
pic.twitter.com/9G0NUA5QAd

— Killa 🌺 (@KillaKreww) October 11, 2025

Here's how fans on social media reacted to the race.

One said: "That runner 35 needs to be studied," while another commented: "Crazy how a regular dude almost beat the world's fastest woman with no experience."

A third added: "She wasn't even trying, not out of breath at the end or anything. She was probably told to make it look close. Let's be honest here."

It has been a memorable 2025 for Jefferson-Wooden, who recently opened up about her recent achievements, which include 19 wins from 20 individual races.

Speaking to The Athletic, she said: "It’s a dream come true. I really did everything that I wanted to do this year. I wrote down in my goal book that I want to become a 100m and 200m world champion, and then a 4x100m champion again.”