Roma blew a 3-1 lead to lose 4-3 to Juventus in a crazy game at the Stadio Olimpico.
The Giallorossi went 1-0 up through Tammy Abraham before Paulo Dybala levelled matters in the 18th minute.
Roma then struck twice early on after half-time through Henrikh Mkhitaryan and captain Lorenzo Pellegrini, who bent in a glorious free-kick from range.
But Juve mounted an incredible comeback, scoring three goals in seven minutes.
Summer signing Manuel Locatelli pulled one back, Dejan Kulusevski notched the equaliser and then Mattia De Sciglio completed the dramatic turnaround in the 77th minute.
That wasn't the end of the drama, though. Matthijs de Ligt was sent off for handling the ball in the area and a penalty was awarded to the hosts.
Pellegrini stepped up but unlike his previous set-piece effort, the Italian's spot-kick was tame and Wojciech Szczęsny saved before the rebound was put wide.
Jose Mourinho's interview and press conference promises to be very spicy indeed.
Roma find themselves lurched in eighth place in Serie A, level on points with city rivals Lazio.
Juventus are in fifth place and underachieving but the incredible win for Max Allegri's men at least means they are six points ahead of Roma.
Featured Image Credit: Image: BT Sport
Josh Lawless