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Guerrero won a battle royal to earn the chance to face a young Lesnar at 2004's No Way Out pay-per-view on February 15.
What followed was the performance of a lifetime as Guerrero won the gold in what was a massive upset.
Check it out below.
Eddie Guerrero won the WWE Championship :goat:
A phenomenal story. A phenomenal match. A phenomenal performer.
We miss you, Eddie :rose:pic.twitter.com/UETtBkOENS
- WWE on BT Sport (@btsportwwe) February 15, 2021
The 30 minute spectacle largely consisted of Lesnar decimating his much smaller opponent, but 'Latino Heat' was not giving up easy.
While he needed a bit of assist from an interfering Goldberg who hit Lesnar with a brutal Spear, this was all about Guerrero.
Ever the opportunist, Eddie looked to capitalise and cover his opponent but the Beast kicked out at two.
When Lesnar went to put his opponent away with a second F5, Guerrero produced one of the greatest counters ever seen in professional wrestling when he reversed the maneuver into a DDT onto the championship belt - the referee still out and oblivious to what was going on.
Guerrero then climbed to the top rope and with the rabid fans on their feet, delivered his tried and trusted Frog Splash and got the referee to count the pinfall to pick up the unlikeliest of victories and cement his place as one of the very best in-ring performers in history.
His infectious personality, charisma and sheer wizardry in the ring helped Eddie become a real fan favourite - and watching his only world championship win back after all of these years gives goosebumps galore.
His first walk to the ring as the champ is equally as emotional, given that Eddie had such an incredible connection with WWE fans and was taken from us far too soon.
Following on from the big win, Guerrero would successfully defend his crown at Wrestlemania against Kurt Angle, while Goldberg and Lesnar would have an absolute stinker of a match on the 'Grandest Stage Of Them All' and both men left the company after the match, which was riddled with boos and groans from the fans in attendance.
Guerrero lost his title to JBL later that year, before turning on Rey Mysterio in 2005 to start a storyline that saw the two fight over the custody of Rey's real-life son Dominik.
He lied, he cheated, he stole and he won the WWE Championship.
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