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McGregor's switch to boxing in August 2017 did lots of things, especially making him a lot of money, and one of those was start a feud between the Irishman and rapper 50 Cent.
The American's friendship with Floyd Mayweather ended up getting him caught in some back-and-forth barbs with McGregor, leading to the UFC star to shout, 'What's up New York City! 50 Cent's a bitch!' during the press tour for the boxing fight.
'50' was asked a month after the fight about the call out and he revealed, via MMA Mania, that he thought he could take 'the Notorious' in a fight, "I was like, dude, this fool didn't know if he was fighting Floyd or me," he told Watch What Happens Live with Andy Cohen.
"I was like, 'Where did that come from?'- you know? But he was doing his job; he was putting on a show and making sure everybody was paying attention.
"In the street? Yeah! C'mon, he weighs 150 pounds, man!"
The feud is far from dead either. Speaking last October at a press conference in Moscow, where the former two weight UFC champion confirmed he'd be returning to the octagon, ahead of January's fight with Donald Cerrone, McGregor was asked about what celebrity he'd like to fight, "I'd have to probably say 50 Cent, I'd like to fight him.
"Throughout the course of the [Floyd] Mayweather build-up I used him as a tool, a promotional tool on the free also, I knew he was linked to Floyd so I tied him in also and he responded big time and we capitalised on that audience so I was very thankful.
"But then after that he began a little tirade against me on social media, particularly Instagram where he'd make these memes about me constantly.
"Every time I'd go onto the internet I'd see 50 Cent had posted up some new stupid meme and I wrote one of the memes - 'old man on the internet making memes' and then he blocked me.
"So he's had to block me, and I still see sometimes, I still get tagged in - other people saying he's saying this and his saying that.
"So I'd like to have a knock-off with 50 yeah, so if you're listening 50 - let's get it going bud."
McGregor was successful in his return to action, beating 'Cowboy' Cerrone inside a minute of their welterweight fight at UFC 246.
On Sunday ESPN's Ariel Helwani suggested that could open the way to Notorious facing Nate Diaz in a trilogy fight this year, although we'd take a fight against 50 Cent too.
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