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In his first fight since his submission loss to lightweight champion Khabib Nurmagomedov at UFC 229 in October 2018, McGregor was straight out of the blocks in his main event welterweight bout with 'Cowboy'.
The Notorious put it on his opponent from the off in Las Vegas and it was his shoulder that proved to be his secret weapon inside the Octagon.
McGregor smashed Cerrone, the man with the most finishes in UFC history - with a number of shoulder strikes in the clinch - breaking his nose and possibly even his cheekbone in the process.
A brutal knee, a couple of precise head kicks and ground and pound brought about the stoppage from referee Herb Dean, who had no choice but to intervene and award McGregor his 22nd victory in MMA.
In slow-mo, you see just how much punishment McGregor inflicted on Cerrone and how he put him away inside 40 seconds after 15 months away.
The veteran Cerrone admitted the approach from McGregor was not something he was prepared for.
"He got me with an elbow straight away and then he headkicked me," Cerrone said post-fight, as per Metro.
"I have never seen anything like the shoulder shot he hit me with. I was disorientated. Then he stepped back, I was bleeding and he head kicked me."
McGregor, meanwhile, was understandably overjoyed with his incredible creativity paying dividends.
"I've been banging people with the shoulder for a while now," he explained to BT Sport after the fight.
"I caught him off guard. I knew because he kind of froze. When I hit the first one I kind of felt like it was a good connection. Yeah, it's a good shot of mine."
Fans were hoping it was the start of a special 2020 for the UFC's first ever two-weight world champion but it wasn't to be.
However, he will be back in the Octagon this coming weekend when he rematches Dustin Poirier in the UFC 257 main event on 'Fight Island'.
Said to be in the best shape of his career for the lightweight encounter, McGregor has promised "a masterpiece".
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