The Champions League returns tonight following the international break, and the Manchester sides are both in action.
Manchester City travel to France to face Lyon, while Man United host Young Boys in their penultimate group games.
Pep Guardiola's men slipped up at home to Lyon in one matchday one as they lost 2-1, however, they have won both games since and a win tonight would guarantee top spot with a game to go.
The Olympians have only lost once in their last 10 games at home to English sides in the competition (W3, D6, L1), although 13/2 says they pick up all points tonight, while a draw is 9/2.
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City (2/5) have scored 21 times in their last five games and are even money to beat Lyon minus a goal.
David Silva has netted four goals in his last four outings, opening the score in the last occasions. 17/2 says Silva opens the scoring again tonight, while it's 9.79/1 that the Spaniard bags first and City win the game.
Former Man United forward Memphis Depay and Citizens talisman Sergio Aguero to get a goal each and four+ corners each is a tempting 14/1 with Paddy Power.
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Jose Mourinho's side will qualify to the knockout rounds tonight with a win over Young Boys, as long as, Valencia fail to get a result against Juventus.
United haven't been at their best season, however, they comfortably seen off Young Boys in the reverse fixture (3-0), and 21/10 says that the Red Devils win minus two goals again tonight against the weak opposition.
Paul Pogba scored twice and grabbed an assist in the away fixture and is 13/2 to open the scoring again tonight and 9/5 to find the back of the net at any point.
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Man United to win to nil; Pogba to score and Young Boys centre-back Steve Von Bergen to be carded is a juicy 33/1 with Paddy Power.
Elsewhere, there are six other games in the Champions League tonight:
AEK Athens (11/2) v Ajax (4/7)
CSKA Moscow (4/5) v Plzen (4/1)
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AS Roma (5/2) v Real Madrid (11/10)
Bayern Munich (3/10) v Benfica (10/1)
Hoffenheim (7/10) v Shakhtar (18/5)
Juventus (2/5) v Valencia (8/1)
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