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The Spaniards' preparations for the tournament were thrown into disarray when captain Sergio Busquets tested positive for coronavirus, followed by Leeds defender Diego Llorente earlier this week.
The squad missed Tuesday's warm-up match against Lithuania in order to isolate, with the Under-21 team deputising.
And a decision has since been made to vaccinate the whole squad, with the players getting their first jabs at the Central Defense Hospital on Friday morning.
Los jugadores de la @SeFutbol reciben su vacuna contra el Covid-19 en la Ciudad del Fútbol.
Miembros de la Unidad de Seguridad del Hospital Central de la Defensa se han desplazado a Las Rozas para administrar los viales indicados.
:information_source: https://t.co/lOdM6GOCw9#SomosEspaña pic.twitter.com/DGDNKfh4Cf
- Selección Española de Fútbol (@SeFutbol) June 11, 2021
A statement from the Spanish FA read: "The purpose of this vaccination is to make it easier for Spain to play Euro 2020 with full security guarantees in addition to allowing the national team to compete on equal terms with other participating teams that have already been immunised."
Boss Luis Enrique will now be hoping his players avoid any potential side effects from the jabs ahead of the clash with the Swedes.
Speaking earlier this week, he said: "The [Spanish football federation] president [Luis Rubiales] asked about the possibility of a vaccine two months ago more or less, with the idea of doing the whole process when the squad list was given.
"Unfortunately, it wasn't possible. We accepted that, we didn't complain.
"I would have liked it to have been done when it should have been done, after giving the list. We have to know that there could be side effects.
"There could be symptoms and issues, and that would really be bad for someone to have symptoms after the vaccine."
Busquets and Llorente have returned two negative tests each, permitting them to resume training, while Spain announced on Friday that there were no positive cases for a third consecutive day.
On Busquets, Enrique said: "It's not that I want to wait for him; it's that I will wait for him. I will wait for all of them."
Sweden have also been rocked by two players - Dejan Kulusevski and Mattias Svanberg - testing positive.
Scotland had a positive case ahead of the 24-team tournament as well.
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