Sancho last played in a DFB-Pokal match against Borussia Monchengladbach in March, he scored the winner before going off injured.
The injury saw him miss the entirety of the Champions League quarter final tie against Manchester City and England's World Cup qualifiers last month, with teammate Jude Bellingham shining in both.
However he returned to action on Wednesday night as Dortmund welcomed Union to the Signal Iduna Park, as they continue to attempt to climb back in the Bundesliga top four to qualify for next season's Champions League.
The 21-year-old came on in the 59th minute, which would have annoyed any Fantasy Bundesliga players with Thorgan Hazard in their team, and pulled off a wonderful nutmeg on Christopher Trimmel.
The reaction of Trimmel's teammate, seeing the action unfold up close, perfectly summed up the mood.
Trimmel, or Union manager Urs Fischer, might have been thinking of the famous quote by Bill Shankly to Tommy Lawrence, after the Liverpool keeper had let a shot go through his legs.
"Sorry, boss, I should have kept my legs together," the keeper said to the legendary Liverpool manager after the game.
"No, Tommy, your mother should have kept her legs together!" the famous Scottish manager brilliantly retorted!
Marco Reus scored the first goal of the game after 27 minutes and Raphael Guerrero secured the points for Dortmund with just two minutes remaining.
The win puts them four points behind Eintracht Frankfurt with four games to go, though Dortmund must play Wolfsburg and RB Leipzig, who are both in the top four before then.
Sancho's full highlights video, from just 31 minutes on the pitch, shows why they're in with a better chance of the top four with him in the team.
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