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The Reds launched a successful title challenge last season and captured the Premier League trophy with a whopping 18-point lead over City.
But talkSPORT's supercomputer has predicted that Jurgen Klopp's men will be unable to retain their status as champions by the end of the 2020-21 season.
City, who have strengthened their squad with the likes of Nathan Ake and Ferran Torres, are predicted to finish first and Liverpool to come second.
However, the supercomputer has predicted that Frank Lampard's men will finish third and secure Champions League football.
Manchester United, who finished third last season, are the final team to make the top four and secure their place in Europe's top-tier club competition.
Arsenal are predicted to finish fifth and secure Europa League qualification, while London rivals Tottenham are expected to end the season in sixth place.
Fulham, West Ham and West Brom are the three sides that have been predicted for Premier League relegation.
Posted below are the supercomputer's predictions for the full Premier League table in the upcoming season.
20. Fulham (relegated)
19. West Ham (relegated)
18. West Brom (relegated)
16. Aston Villa
15. Crystal Palace
11. Sheffield United
8. Leicester City
5. Arsenal (Europa League qualification)
4. Manchester United (Champions League qualification)
3. Chelsea (Champions League qualification)
2. Liverpool (Champions League qualification)
1. Manchester City (Premier League champions)
Featured Image Credit: PA
Topics: Manchester City, Liverpool, Wolverhampton Wanderers, Football News, Aston Villa, Leicester City, Chelsea, Tottenham Hotspur, Football, West Bromwich Albion, Manchester United, Brighton and Hove Albion, Sheffield United, Southampton, Premier League, Everton, West Ham United, Leeds United, Arsenal, Burnley, Fulham, Newcastle United, Crystal Palace
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