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Quique Setien was swiftly dismissed as manager after the Blaugrana experienced one of their most damaging defeat and a serious rebuilding job is on the cards under Ronald Koeman, with the former Barca defender expected to be announced as the new boss.
And according to Mundo Deportivo, Barca are genuinely willing to offload the bulk of the squad this summer - except a select group players.
Lionel Messi is the number one on the 'keep' list despite him reportedly wanting out of the Nou Camp after the latest dismal defeat, with goalkeeper Marc-Andre Ter Stegen also seen as indispensable.
Barca also want to retain Frenkie De Jong, who they still have plenty of confident in even with his inconsistent form following his big-money move from Ajax, as well as exciting wonderkids Ansu Fati and Riqui Puig.
That key five are safe this summer but the same cannot be said for the rest.
Luis Suarez has been heavily linked with a return to former club Ajax as Barca chase Inter's Lautaro Martinez, £107 million signing Antoine Griezmann will be allowed to go if Barca get the fee they are looking for - while compatriots Samuel Umtiti and Ousmane Dembele are also unwanted due to their "injury and attitude problems".
La Masia products and long-time players Sergio Busquets, Sergi Roberto and Gerard Pique - the latter even putting himself on the transfer list in an emotional interview on Friday night - may also be out the door.
Ivan Rakitic wants to head back to Sevilla even though his former employers don't wish to pay any money but he too is slated to leave along with midfield partner Arturo Vidal.
Frankly Barcelona need these wholesale changes or else they risk experiencing an AC Milan level of decline.
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