| Last updated
And Ole Gunnar Solskjaer's men now turn their attention back to the Premier League, with United sitting two points ahead of Manchester City in the table.
Sheffield United defeated Plymouth Argyle 2-1 at Bramall Lane in their fourth-round FA Cup clash.
The Blades have struggled in the league this season and currently sit bottom of the table on five points.
Here is how to watch the Premier League match LIVE in the United Kingdom.
United and Sheffield will clash at Old Trafford on 27th January.
United vs Sheffield will be shown LIVE on BT Sport 1 HD and BT Sport Ultimate.
Sky customers can watch BT Sport 1 on channel 413.
BT Sport Ultimate can be accessed using channel 433 via BT TV, as well as being available on the BT Sport app.
Fans can watch the Premier League clash LIVE using BT Sport's website or using the broadcaster's official app.
The app can be downloaded on PlayStation and Xbox consoles, NOW TV and iOS and Android devices, along with supporting functionality with Chromecast and Airplay.
United vs Sheffield will kick-off at 8:15pm at Old Trafford.
Coverage for the match will begin from 8pm on BT Sport 1 HD and BT Sport Ultimate.
BT Sport has the rights to broadcast 52 Premier League matches LIVE for the 2020-21 season.
There are four other Premier League matches that will be shown on Wednesday.
Burnley vs Aston Villa and Chelsea vs Wolverhampton Wanderers will both kick-off at 6pm UK time.
Brighton welcome Fulham to the Amex at 7:30pm, while Everton will host Leicester City at Goodison Park for their 8:15pm clash.
Featured Image Credit: PA
Chosen for YouChosen for You
Most Read StoriesMost Read