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The 23-year-old defender was in immediate pain after pulling up in the session at St George's Park, with manager Gareth Southgate revealing nobody was around him.
In an update on their official website, Liverpool have said Gomez's surgery to repair a tendon in his left knee has gone well and there was no damage done to his ligaments.
Still, the former Charlton Athletic man is facing another lengthy spell on the sidelines as a result of the latest unfortunate set-back.
.@J_Gomez97 has today undergone successful surgery to repair a tendon in his left knee.
The issue was isolated to Gomez's tendon, with no damage to any other associated knee ligaments and Joe will now begin a rehabilitation programme with our medical team :muscle:
- Liverpool FC (@LFC) November 12, 2020
An update on @J_Gomez97, who has undergone successful surgery on the knee injury he sustained in #ThreeLions training yesterday.
Come back stronger, Joe :muscle: https://t.co/qKyxpNNkav
- England (@England) November 12, 2020
A statement from Liverpool explained: "Gomez will begin a rehabilitation programme with the Reds' medical team immediately, with club staff carefully monitoring his progress.
"No timescale is being placed upon his return, though the issue is likely to rule him out for a significant part of the remainder of 2020-21."
Gomez is the latest casualty in what has developed into quite the njury crisis at Liverpool, particularly in defence.
His regular centre-back partner Virgil van Dijk may well not feature for the Premier League champions again this season after undergoing knee surgery as a result of a wild challenge from Jordan Pickford in the Merseyside derby.
Fabinho had been deputising in defence prior to suffering a hamstring injury, while Trent Alexander-Arnold was forced off with a calf problem in the 1-1 draw with Manchester City on Sunday.
At the moment, Liverpool's only options to play at centre-back are academy products Rhys Williams and Nat Phillips, as well as Joel Matip - a player who has struggled with injuries during his time at Anfield.
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