Inter host Juventus in the first Derby d'Italia of the season, with the Nerazzurri hoping to maintain their 100% record at the beginning of the Serie A season.
Antonio Conte welcomes his former team to the San Siro for the first time since taking charge in Milan and his team are the only side left in Italy's top tier to have won all their games.
Juve have been named champions of Italy for the past eight years and Maurizio Sarri won't want to be the manager to end that run.
It is the 236th time the two sides have met in an official game.
What time is kick-off?
The game will begin at 7.45pm UK time on Saturday.
Italy is one hour ahead of British time, meaning a 8,.45pm local time kick-off for the players in Milan
What TV channel is it on?
Premier 2 will show the action LIVE in the United Kingdom on Sunday - available on Sky channel 429.
Viewers can also stream the action online at www.premierplayer.com.
Premier Sports will show games across Premier 1 and Premier 2 every week.
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