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Germany fought back against Hungary at the Allianz Arena to secure a 2-2 draw in their final Group F clash at Euro 2020.
Joachim Low's side finished second in Group F behind 2018 World Cup champions France, but Germany will now face England at Wembley in the round of 16.
Germany could be without Gundogan and Rudiger for their upcoming match after the pair missed out on training, according to reports.
Gundogan, 30, has started all three of Germany's Euro 2020 matches alongside Real Madrid star Toni Kroos in midfield.
German TV channel Sport1 now reports that the Manchester City midfielder is suffering from a cranial bruise.
But it is unknown when Gundogan, who was superb for the Premier League champions last season, picked up the knock.
Rudiger, much like Gundogan, has been an integral part of Low's Germany XI for this summer's Euros.
However, the 28-year-old Chelsea defender was also absent from Germany's training amid rumblings that he is suffering from a cold.
Gundogan and Rudiger are still expected to travel with the Germany squad to London for the knockout stages.
Low, who will step down as Germany head coach after Euro 2020, will hold his side's final training session on Monday in Germany before they fly out to London.
Liverpool manager Jurgen Klopp has insisted it would be "crazy" to write off Germany against England.
When asked about Germany's chances of reaching the quarter-finals, he told Bild: "To write off Germany now, it would be crazy.
"We played well against France, Portugal we dominated like hardly any other opponent in recent years.
"We struggled against Hungary, yes. But nothing more happened. Sometimes as a team you need such a game.
"And now we're going to make a real go of it on Tuesday."
Featured Image Credit: PA
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