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After a slow opening, Marcus Rashford's solo strike had given Manchester United the lead at Old Trafford on the half-hour mark.
However six minutes later, when Maguire attempted to flick a cross clear inside the United penalty area, his weak header fell right at the feet of Saint-Maximin who fired into the roof of David de Gea's net.
It was admittedly a difficult header to get right for Maguire. But heading it out for a corner - or literally anywhere that wasn't right into Saint-Maximin's path - would probably have been preferable.
That left the Premier League game 1-1 at half time and had some football fans once again pointing the finger at Maguire for a costly defensive error that led to a goal.
Harry Maguire is one of the biggest problems at this club. You can't have a player who is undroppable because of his captaincy and price tag. That was a woeful header #MUFC- Shawn :red_circle::white_circle::black_circle: (@RealDevils1) February 21, 2021
It is Maguire's fault 100%. Stop pinning it on De Gea.- Himansh (@HimanshSingla_) February 21, 2021
The 27-year-old has had occasional struggles, on and off the pitch, since he arrived from Leicester for £80 million in 2019.
However the England centre-back has largely looked solid of late, particularly alongside Eric Bailly in defence.
But the reaction to his latest error - if that's how you view the attempted header clear from a difficult position - shows there's still plenty of Man United who still are not convinced by Maguire.