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Brendan Rodgers' Foxes have enjoyed a stellar few seasons and will be eager to crown their good form with silverware.
The Foxes beat the Blues 2-0 earlier this season in the Premier League and their return meeting was scheduled for the same day as the cup final in a strange twist of fate.
That match has now been scheduled for just a few days later on Tuesday, May 18 but who will be the FA Cup holders when that league game comes around?
The FA Cup final is on Saturday, May 15 and the match is set to kick off at 5.15pm.
The match will be broadcast live on BBC One, BBC iPlayer, BT Sport 1 and BT Sport Ultimate.
Chelsea are 10/11 to win, with Leicester City priced at 29/10 to come away with the victory. A draw is priced at 13/5.
Odds are correct at the time of publication and are, as always, subject to change.
Please gamble responsibly. For more information visit: https://www.begambleaware.org.
Since Thomas Tuchel's appointment, Chelsea's defence has been the meanest in the country and the way the Londoners brushed Real Madrid aside in the Champions League semi-final was seriously impressive.
Leicester are having another superb season under Brendan Rodgers and look set to cap a fine Premier League campaign with a top-four finish, and with Jamie Vardy and Kelechi Iheanacho in their ranks, they can trouble any team.
But Tuchel's well-drilled outfit are trusted to keep Leicester at bay while Mason Mount, who has been in scintillating form, will lead the charge for Chelsea's attack.
Half-Time/Full-Time: Chelsea/Chelsea 2/1
Chelsea have to put Wednesday's shock defeat by Arsenal behind them and we expect them to lead from start to finish here.
Tomorrow is the first of four 'finals' for Tuchel's men as they aim to finish the season by winning two trophies and secure a top-four place.
They have no time to feel sorry for themselves against a buoyant Leicester, who go into the game on the back of a crucial win against Manchester United.
To score anytime: Mason Mount 16/5
Mason Mount is becoming a big-game player for the Blues.
But while Mount has impressed in attack, Chelsea have struggled with goal conversion in recent months.
Chance after chance passed them by in their Champions League semi-final second leg against Real Madrid.
Of their 15 shots, only five were on target - two of which were goals - while eight ended up being off-target.
To be booked: Jorginho 5/2
Having been an unused substitute for Chelsea's last two matches against Leicester, Jorginho will be itching to help the team on Saturday - and his card record against the Foxes is remarkable.
The Italian has been booked in each of the last three matches he has started against the Foxes, and we're backing him to make that four in a row as he tries to deal with their counter-attacks.
Tuchel confirmed the double injury boost in his pre-match press conference at Cobham on Friday afternoon where he also revealed no fresh concerns.
Kovacic has missed The Blues' last eight games across all competitions with a muscle problem, while Kante didn't feature in the 1-0 loss at the hands of Arsenal because he was carrying an Achilles injury and was not risked.
However, both players are in contention to start against the Foxes in what Tuchel has explained is the first of two 'finals' with the sides set to meet in the Premier League next week.
Leicester are sweating on the fitness of defender Jonny Evans.
The centre-back was forced off in the defeat to Newcastle United earlier in the month with a heel problem and has since sat out the following two games.
He is being assessed and boss Rodgers admits he will give Evans every chance to prove his fitness ahead of Saturday's game.
Meanwhile, Cengiz Under has been nursing a hip problem while Harvey Barnes and James Justin remain out along with Wes Morgan.