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Gareth Southgate's men will be eyeing up a semi-final spot in back-to-back major international competition with a win over the Ukrainians. No pressure, lads.
More importantly, a win over Ukraine will see England return to Wembley Stadium - the home of English football - where the remainder of the tournament will be held, including the final. Imagine the scenes.
In an interesting twist, the referee for England vs Ukraine is German, as is the whole officiating team.
So far, England are still unbeaten and are yet to even concede a goal - is it, for real, coming home this time?
We'll face Ukraine in Rome on Saturday for a place in the last four of #EURO2020 pic.twitter.com/F45yjxUtEZ
- England (@England) June 29, 2021
Ukraine progressed to the last eight with a goal in added time at the end of extra time against Sweden on Tuesday - and they are a team not to be taken lightly.
With the quarter-finals now underway, our tipster Robert Mann takes a look at some of the best bets from England vs Ukraine to get your teeth stuck into.
England are 2/5 to win, with Ukraine priced at 15/2 to come away with the victory. A draw is priced at 10/3.
Prediction: 2-0 (5/1)
Half-Time/Full-Time: England/England (11/10)
The Three Lions, which boasts one of its most youthful and attacking sides in years, are now considered to be the main threats during this year's contest - we reckon they could make a statement against Ukraine tonight.
We're predicting that England will head into half-time in the lead and will then go on to punish the Ukrainians further in the second half. It's easier said than done, but we think it's a solid bet.
First Goalscorer: Harry Kane (23/10)
Harry Kane finally bagged his first goal of the tournament against Germany on Tuesday and his header served as a solid reminder that he thrives on getting the right service.
Kane was the Premier League's top scorer last season and Ukraine are far from watertight at the back - and for that reason, we're backing the England skipper to draw first blood tonight.
Ukraine have conceded six goals in four matches, including three against the Netherlands. Kane, they're all yours, mate.
To win to nil: England (11/10)
England beat Ukraine at Euro 2012 thanks to a solitary goal from Wayne Rooney and we expect them to do the same on Saturday and win without conceding again.
Gareth Southgate's men will be approaching tonight's match in Rome with confidence after keeping four successive clean sheets in the tournament - making the Three Lions the only team yet to concede a goal. Impressive.
Taking that into account, England to win to nil sounds like a given, doesn't it? Especially after Ukraine's draining quarter-final against Sweden.
Odds are correct at the time of publication and are, as always, subject to change.
Please gamble responsibly. For more information visit: https://www.begambleaware.org.
Final session before Ukraine: :ballot_box_with_check:
Next stop: :flag_it: pic.twitter.com/BsQIClPtJL
- England (@England) July 2, 2021
Gareth Southgate's shift to a back three worked wonders against Germany and may therefore be deployed here once again. It could, however, hinder Jack Grealish's chances of a deserved start.
Artem Besedin was the victim of a horror challenge by Sweden's Marcus Danielson in their quarter-final, with fears that he could remain sidelined until 2022.
:blue_heart::yellow_heart: Останні новини:
:white_check_mark: Збірна вже в Дніпрі
:white_check_mark: Команда провела тренування на "Дніпро-Арені"#МиЗбірна pic.twitter.com/V5acg7c5Cf
- Ukrainian Association of Football (@uafukraine) September 9, 2019
Elsewhere, Oleksandr Zubkov is reported to have recovered from a calf strain and could put his name in the hat for selection, while Denys Popov has been forced to withdraw through injury.
Artem Dovbyk's heroics may not be enough to earn him a start over Andriy Yarmolenko and Arsenal-linked Roman Yaremchuk, although the West Ham United man was cautioned in the last-16 win.
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