Mayweather, 44, dominated Paul over the course of their eight-round fight in June at the Hard Rock Stadium in Miami, Florida.
However, the American superstar was unable to knock out Paul or force a stoppage, despite no official winner being declared from the contest.
Mayweather was met with criticism for failing to KO the 26-year-old YouTube star, but the boxing legend was unfazed after walking away with a hefty $100m from the fight.
Tyson predicted ahead of Mayweather vs Paul that the unbeaten former five-weight world champ would "beat his f****n' a**e" in the fight.
The 55-year-old American star made his sensational return to the squared circle against fellow boxing legend Roy Jones Jr in an exhibition fight in November 2020.
Tyson claimed that his fight against Jones was "not right" and it was "damaged," comparing his experience to Mayweather's clash against Paul.
Speaking on Hotboxin' with Mike Tyson, he said: "You see, Floyd [Mayweather], he is damaged.
"He is damaged. He wants to come back and fight. You see, that's what that does.
"I came back, that's not right. It f***s you up. It is damaged.
"Listen, I didn't feel that way, I never wanted to do this s**t again, and I don't know what it is, I wish I could, but I'm just taking advantage of what this game is, you get me?"
Despite Tyson's comments over the Jones fight, Iron Mike has revealed plans to return to the boxing ring for another exhibition showdown.
The Baddest Man on the Planet told TMZ in April that he plans to take on fierce rival Lennox Lewis after his trilogy fight with Evander Holyfield collapsed.
"I'm gonna fight Lennox Lewis. September," Tyson said.
Featured Image Credit: Hotboxin' with Mike Tyson/PA
Chosen for YouChosen for You
Most Read StoriesMost Read