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The 44-year-old American superstar clashed with McGregor in a blockbuster crossover super-fight in 2017.
Mayweather stopped the 32-year-old Irishman in the 10th round of their Las Vegas bout to notch up his unblemished 50-0 boxing record.
The boxing legend announced his retirement from the sport in 2017, but he returned in 2018 to destroy Japanese kickboxer Tenshin Nasukawa in an exhibition fight.
Mayweather will once again return to the squared circle on 6th June for his exhibition bout with Paul at the Hard Rock Stadium in Miami, Florida.
Speaking ahead of the Paul fight, Money accused his rivals of 'stealing his blueprint' and 'hating on him.'
However, Mayweather hinted that a rematch with McGregor could happen down the line.
"Absolutely. He [is] easy," he told Showtime Sports.
"The beef is all these guys look up to me, steal my blueprint and then get to hating on me."
McGregor, who returns to MMA action on 10th July at UFC 264, has continued to taunt Mayweather since their 2017 mega-fight.
The Notorious has been open to the idea of a rematch, even promising boxing legend Mike Tyson he would "crack the puzzle" and "beat" Mayweather in a second fight.
Mayweather Promotions CEO Leonard Ellerbe also hit out at McGregor by suggesting that a rematch could be on the cards, saying that "things are a little different now."
He told Showtime Sports: "When I say to Conor, if you're listening. You can get that, too.
"Most definitely. That right there is very personal.
"After everything, where they left the ring, they hugged, but things are a little different now."
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