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The fight, taking place at the Tottenham Hotspur Stadium, sees Joshua take on the man who formerly reigned as undisputed cruiserweight king.
Usyk has yet to be defeated in his 18 fights in the pro ranks but has only fought twice at heavyweight, against Chazz Witherspoon and Dereck Chisora.
Joshua, meanwhile, is on something of a resurgence after avenging his only career defeat to Andy Ruiz Jr and then knocking out Kubrat Pulev in some style.
When is Joshua vs Usyk?
Anthony Joshua vs Oleksandr Usyk is on Saturday, 25th September.
What time does the undercard start?
The card is expected to begin at around 6pm UK time.
Who is on the undercard?
Where is Joshua vs Usyk taking place?
At the Tottenham Hotspur Stadium in North London.
What time are Joshua and Usyk expected to walk to the ring?
The main event is expected to take place any time from 10.30pm UK time.
How do I watch Joshua vs Usyk?
In the UK, the fight will be on Sky Sports Box Office for £24.95, and in 170+ countries around the world it'll be streamed live on DAZN.
Joshua vs Usyk prediction:
Joshua to win this one by late stoppage.
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