The YouTuber takes on former UFC star Woodley on Sunday evening in an attempt to take his unbeaten record to 4-0.
He made his name on social media platform Vine back in 2013 before starring on the Disney Channel as a teenager.
Paul then started his YouTube channel and split from Disney due to the two brands clashing.
From there his channel grew to the point he started outside ventures, including exhibition boxing bouts.
He defeated KSI's younger brother, Deji, on the undercard of KSI's fight with Logan Paul in 2018 and didn't look back.
The 24-year-old turned pro and defeated AnEsonGib, Nate Robinson and Ben Askren to stay undefeated.
Sunday's clash with Woodley promises to be his toughest task yet, with Woodley a former welterweight champion.
Many believe Paul is only involved in boxing as a publicity stunt - but the 'Problem Child' takes it very seriously.
He told the Daily Mail earlier this year: "I'm training daily, sometimes six, seven days a week. I'm doing sprints, I'm jogging five, six, seven miles.
"I'm doing thousands of push ups, abs every day, neck exercises... I'm boxing, hitting the heavy bag, hitting the speed bag, I'm sparring 2-3 times a week against world champions, I'm doing yoga.
"I'm eating chicken and vegetables and cutting out all the bad stuff.
"I'm completely sober and I'm only allowed to have sex once a week!"
On the undercard this weekend is Tommy Fury's clash with Anthony Taylor, with Paul having a feud with the former on social media.
Paul said: "Most people sit up here like Fury and he's like 'Oh, I have a tough opponent.' No, when I know what's going to happen, when I'm confident in my skill, I'm already thinking about the next opponent.
"Why do you think this guy (Fury) is sitting behind me right now?"
And without hesitation, Fury fired right back.
"Your time is coming pal," he said.
"Don't mention my name out of that garbage mouth of yours."
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