Kyle Walker and Eric Dier are on course to leave Tottenham this summer, according to Ladbrokes.
Walker has been cut from 8/11 to 1/5 to join Manchester City, after the Citizens missed out on Dani Alves.
While Pep Guardiola makes a beeline for Walker, Jose Mourinho is set to do likewise for Eric Dier.
Amid reports that United are willing to offer £50m for the England international, the bookies have chopped the odds from 5/2 to just 7/4 on Dier moving to Manchester.
And a former United hero could be returning to these shores, with Robin van Persie just Evens to make a Premier League comeback this summer.
Ladbrokes News' Richard Marsh said: "These are worrying times for Tottenham fans, and the latest odds suggest both Walker and Dier are edging closer and closer to Manchester."
Ladbrokes Latest Betting:
Summer 2017 transfer specials
Kyle Walker to join Manchester City - 1/5
Eric Dier to join Manchester United - 7/4
Robin van Persie to join any Premier League club - Evens