Ladbrokes have cut the odds of Man United beating Tottenham Hotspur this weekend, following the announcement that Harry Kane will miss the game through injury.
The bookies can report a huge increase in interest on Friday afternoon on the hosts winning the Old Trafford clash, and odds of them taking all three points have been cut to 11/10 as a result.
Romelu Lukaku - a 7/2 shot for the Golden Boot - is the 10/3 favourite to open the scoring, while at 5/1, Fernando Llorente is the most likely man to find the net for the visitors in Kane's absence.
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Alex Apati of Ladbrokes said: "Spurs have been dealt a huge blow 24 hours before the biggest game of their season so far, and it's something punters have jumped on with plenty fancying Mourinho's men to inflict more misery on the North Londoners."
Ladbrokes Latest Betting
Man United v Tottenham Hotspur
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Man Utd to win - 11/10
Spurs to win - 13/5
Draw - 11/5
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First Goalscorer
Lukaku - 10/3
Llorente - 5/1
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Rashford - 11/2
Martial - 6/1
Alli - 13/2
Son - 7/1
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Mkhitaryan - 15/2
No Goalscorer - 15/2
Others on request