Chelsea, Arsenal, Rangers and Celtic are all in Europa League action tonight.
The London sides will secure a place in the first knockout round with wins over BATE Borisov and Sporting Lisbon respectively, while Steven Gerrard's and Brendan Rodgers' men are still fighting for progression.
Chelsea and Rangers kick-off at 17:55 as they are away, and Arsenal and Celtic get the ball rolling at 20:00 as they are at home.
Sarri's side beat BATE 3-1 at Stamford Bridge a fortnight ago as Ruben Loftus-Cheek bagged a hattrick, they are 3/10 to pick up all three points again tonight.
The Belarus champions are 10/1 to cause an upset, while the draw is 5/1.
Chelsea will be without, Marcus Alonso, David Luiz, Antonio Rudiger and Alvaro Morata as the Chelsea boss rested the latter.
Loftus-Cheek is 11/2 to open the scoring and 15/8 to net at any time and Olivier Giroud, who is yet to bag a goal this season, is 11/10 to grab his first at any point tonight.
Eden Hazard, who is returning from a back injury, is also 11/10 to score his ninth goal in all competitions.
The Gers are unbeaten in their 11 last European clashes, however, hosts Spartak Moscow are 5/4 favourites to end their incredible run.
The Ibrox side are 5/2 to board the plane back to Glasgow with a huge three points in the bag, the reverse fixture ended goalless and a draw again tonight is 12/5.
Rangers are second in Group G with five points and Moscow sit bottom with just two, so the tie could be considered make or break for the Russians.
Spartak are also on a four-game losing streak at home and considering Rangers European form they might be worth backing at 5/2.
Striker Alfredo Morelos has four goals in the competition so far this season, the Colombian is 13/8 to score anytime tonight in the Russian capital and 9/2 to fire Rangers into the lead.
The Gunners, who are on a 15-game unbeaten run across all competitions, are 1/4 to do the double over Sporting as they beat them 1-0 in the reverse fixture.
The Portuguese side a massive 10/1 to pick up the three points at the Emirates, while a draw is 5/1.
In-form forwards Alexandre Lacazette and Pierre-Emerick Abameyang are 5/6 and 8/11 to score at any time and both can be backed at 3/1 to open the scoring.
Celtic face the tough task of Red Bull Leipzig at Parkhead. The Hoops lost 2-0 when they travelled to Germany a couple of weeks ago.
Rodgers' side need to avoid defeat tonight to keep their hopes of progression alive and are 27/10 to beat Leipzig, while the draw is 13/5.
The visitors are decent odds at 11/10 to win tonight, considering they are unbeaten in their last 10 games with seven wins and three draws.
Jean-Kevin Augustin is 7/5 to score his fourth goal in Europe at any point in the 90 minutes and 9/2 to give the away side the lead.
Celtic forward Odsonne Edouard is 21/10 to find the net for just the second time in the competition at any time, while he is a 6/1 to bag first.
A Chelsea, Rangers, Arsenal and Celtic accumulator returns £367 from a £20 stake.