Following the shock appointment of Claudio Ranieri this morning, the Cottagers are the first side since Leicester City back in 2015-16 to be 5000/1 to lift the Premier League trophy.
Slavisa Jokanovic was sacked following Fulham's awful start to the season which saw them pick up just one win in their first 12 league games, they also suffered their seventh straight defeat away to Liverpool on Sunday.
Things had been going dreadfully for Jokanovic. Image: PA Images
Ranieri famously defied the odds with the Foxes when he won the league with the Midlands side, however, his most important job this season will be saving Fulham from relegation and 7/5 says they avoid the drop this campaign.
While, you can back Ranieri at 50/1 to somehow miraculously guide the Lilywhites to a top half finish.
It will be the Italians 18th managerial role since he began his career in 1986, he has had spells at West London rivals Chelsea, Juventus and Inter Milan during that period.
Alex Apati of Ladbrokes said: "Ranieri's appointment has forced us to turn our attention to Fulham achieving the unthinkable next season. It's only fitting they're the first team since Leicester to be priced 5000/1 to win the title."
In a statement, Ranieri said: "It is an honour to accept Mr. Khan's invitation and opportunity to lead Fulham, a fantastic club with tradition and history.
"The objective at Fulham should never be to merely survive in the Premier League. We must at all times be a difficult opponent and should expect to be succeed.
"This Fulham squad has exceptional talent that is contrary to its position in the table. I know this team is very capable of better performances, which will work on straight away as we prepare for Southampton at the Cottage."
Ranieri's time at Leicester didn't end well but he did win the Premier League. Image: PA Images
Fulham chairman Shahid Khan said: "I wasn't anticipating having to make this announcement related to Slavisa and wish the circumstances were such that I didn't have to, but our path this season has led me to make what I know is the correct decision, at the right time, for our players, the club and our supporters.
"Slavisa will always have me appreciation and respect for everything he did to return Fulham to top-flight football. I am hoping everyone in the Fulham Family shares my heartfelt sentiments for Slavisa and joins me in wishing him success and good fortune, wherever his next stop may be."