Manchester United manager Ole Gunnar Solskjaer dropped Chris Smalling and Phil Jones for the club's opening game of the season against Chelsea on Sunday afternoon.
The Norwegian instead included Axel Tuanzebe in the 18-man squad, while Harry Maguire and Aaron Wan-Bissaka made their debuts.
United's new defensive duo are joined by Victor Lindelof and Luke Shaw at the back while club captain Ashley Young dropped to the bench.
Paul Pogba, Scott McTominay and Andreas Pereira made up Solskjaer's three-man midfield, while Jesse Lingard, Anthony Martial and Marcus Rashford started up front for the Red Devils.
Plenty of Manchester United fans were delighted with the team sheet ahead of kick-off.
Here is just some of the reaction from Twitter this afternoon:
Manchester United ran riot on Chelsea on Sunday in a thumping 4-0 win to open their Premier League season.
Marcus Rashford gave them the lead from the penalty spot during a close first-half in which Chelsea hit the woodwork twice.
But Ole Gunnar Solskjaer's men pulled away after half-time in devastating fashion on the counter-attack.
Anthony Martial doubled their lead after converting a low cross before Rashford added his second, taking in a delightful long ball from Paul Pogba before sliding it past Kepa.
Daniel James replaced Andreas Pereira in the 74th minute - and his goal rounded off a brilliant opening weekend for Manchester United.